The winner of the 1999 Animal Physiology and Endocrinology Award, Edward L. Squires, is recognized for his highly influential contributions to our understanding of equine reproduction. Squires received a B.S. degree in animal science (1969) and an M.S. degree in reproductive physiology (1971) from West Virginia University. He received his Ph.D. degree from the University of Wisconsin in 1974 and taught at the University of New Hampshire for 2 years. He has been at Colorado State University since 1976. Squires teaches equine reproductive management for animal science students, equine practica for junior and senior veterinary students, and has a major role in organizing 10 continuing education programs annually. He has advised 54 graduate students. He supervises Colorado State University's unique equine embryo transfer program. Hundreds of equine embryos from valuable mares have been shipped to his laboratory for embryo transfer. Nowhere else in the world is there a program of similar scope. Between 1989 and 1999, Edward Squires published 84 papers in refereed journals, 16 chapters in books and proceedings, and 39 articles in popular magazines. His papers report well-designed and carefully conducted experiments in three areas: reproductive endocrinology, embryo transfer and related biotechnology, and artificial insemination. He is especially well known for development or improvement of procedures for superovulation, embryo transfer, production of identical twin foals by splitting embryos, and cryopreservation of embryos and sperm. Squires is among the world's leaders in research on equine reproduction and is a worthy recipient of the Animal Physiology and Endocrinology Award.