Scientific Program

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“Developmental Programming – Putting the Pieces Together”

Sunday August 28, 2022

Welcome and opening remarks, Kristen Govoni, Organizing Co-Chair

Keynote Address- Kevin D. Sinclair,  Professor Developmental Biology, University of Nottingham – “Maternal nutritional effects in developing oocytes and embryo

Monday August 29, 2022

Trainee Workshop 1-Collaborating in Perinatal Biology-with continental breakfast

Session I: What Dad Can Do for You: Paternal Contributions to Offspring Health

Carl Dahlen, PhD, Associate Professor, Animal Sciences, North Dakota State University – “Overview: the paternal contribution to developmental programming”

Hasan Khatib,  PhD, Professor of Genetics and Associate Chair, Department of Animal and Dairy Sciences, University of Wisconsin-Madison “Effects of paternal nutrition on the epigenome and phenotypes of the offspring”

Colin Conine, PhD, Assistant Professor Pediatrics and Genetics, Perelman School of Medicine, University of Pennsylvania, “The transmission of epigenetic information to offspring by sperm RNAs”

Hannah Morgan, PhD, Post-Doctoral Research Fellow, Faculty of Medicine & Health Sciences, University of Nottingham – Dads, diet and development: paternal influences on fetal growth”

Mary Elizabeth Patti, MD, Associate Professor Medicine, Joslin Institute, Harvard University – “Reversibility of Paternal Contributions to Integenerational Inheritance – A New Approach to Metabolic Disease Prevention?”

Break

Session 2 - Male vs Female: is it ever close? Outcomes based on fetal sex

Krithika Lingappan,  MD, PhD, MS, Associate Professor Pediatrics, Perelman School of Medicine University of Pennsylvania – “Sex as a vital biological variable in the newborn lung injury and repair”

Perrie O-Tierney-Gin, PhD, Research Associate Professor, Mother Infant Research Unit, Tufts Medical Center – “Let’s talk about sex – differences between male and female offspring in placental nutrient metabolism and delivery”

Less Myatt, PhD, Professor Obstetrics and Gynecology, Oregon Health Sciences University - “Sexual dimorphism in placental adaptive responses to maternal metabolic disease”

Free time and networking

Session 3Maternal superpower – creating the perfect food: Maternal environment effects on lactation and offspring outcomes

Geoff Dahl, PhD, Harriet B. Weeks Professor, Animal Sciences, University of Florida –“High Impact of high temperature; effect of in utero heat stress in the calf”

Frank F. (Skip) Bartol, PhD, MS, Alumni Professor & Associate Dean for Research and Graduate Studies, College of Veterinary Medicine, Auburn University – “Lactocrine hypothesis – postnatal programming

Brigid Gregg, MD. Assistant Professor of Pediatrics, Division of Pediatric Endocrinology, University of Michigan – Ann Arbor – Early Stage Investigator Speaker.Lactational diet and DOHaD

Ellen Demerath, PhD, Professor of Epidemiology and Community Health, University of Minnesota School of Public Health – “Human milk composition as a link between maternal metabolic status and infant growth and body composition”

Poster Session 1- evening

Tuesday August 30, 2022

Trainee Workshop 2, and continental breakfast

Session 4 – Immunity on the Playground: Inflammation and Immune modulation in the First 1,000 days

Andrea Edlow, MD, MSc, Assistant Professor Harvard Medical School. Massachusetts General Hospital - “Transplacental transfer of maternal immunity: durability and correlates of protection”

Kylie Kavanagh, DVM, MS, MPH, Associate Professor Pathology-Comparative Medicine, Wake Forest University - “Maternal metabolic syndrome and offspring immune activation in old world nonhuman primates”

Ryan Ashley, PhD, Professor, Department of Animal & Range Sciences, New Mexico State University – “The role of the CXCL12/CXCR4 chemokine axis in placental development and fetal health”

Dean Myers, PhD, Associate Vice President for Health Sciences Research, Professor and John W. Records Chair in Maternal Fetal Medicine, Vice Chair for Basic Research, Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center- “The Olive baboon, Western-style diet, maternal obesity and fetal/placental impact: what we are learning along the way about diet versus obesity in a non-human primate”

 Break

Session 5 – Novel Environmental Factors Programming the Offspring

Alison Ward, PhD, Associate Professor, Department of Animal Sciences, North Dakota State University – Early Stage Investigator Speaker. “Mitigating the effects of feed restriction on fetal developmental programming by strategic supplementation of one-carbon metabolites in beef cattle”

Cetewayo Rashid, PhD, Assistant Professor Pharmacology and Nutritional Sciences, School of Medicine University of Kentucky - Early Stage Investigator Speaker. “Organophosphate flame retardants: metabolism disrupting chemicals in adults and offspring”

Folami Ideraabdullah, PhD, Associate Professor, Department of Genetics and the Department of Nutrition at the Gillings School of Global Public Health, University of North Carolina – “Modeling interindividual effects of maternal vitamin D deficiency in the mouse”

Trainee talk- "TBD"

Free time and networking

Conference Dinner and Presentation of Awards

Session 6 - DJP Barker Memorial Lecture

Rebecca Simmons, MD,  Hallam Hurt Professor in Neonatology, Center for Research on Reproduction and Women’s Health at the Perelman School of Medicine, University of Pennsylvania  - “Yin and Yang of Developmental Programming

Poster session 2 evening

Wednesday August 31, 2022

URiS Workshop, and continental breakfast

Session 8 – Heart-felt connections made early in life: Vascular Effects

Emin Maltepe, MD, PhD, Associate Professor, Department of Pediatrics, University of California – San Francisco – “Effects of hypoxia on placental development and role of HIF1a

Caleb Lemely, PhD,  Associate Professor, Animal and Dairy Sciences, Mississippi State University “Placental rhythms and blood flow during compromised maternal nutritional status”

Emily Su, MD, Msc Associate Professor, Divisions of Maternal-Fetal Medicine & Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado – “Human placental villous stromal extracellular matrix regulates fetoplacental angiogenesis in severe fetal growth restriction

Sonnet Jonker, PhD. Associate Professor of Medicine, Center for Developmental Health, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR – “Transience of plasticity in the perinatal heart

Session 9 – Trainee selected Presentations 15-minute presentations

Conference Closure – final comments and election of next Organizing Committee

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