May 06, 2021

Interpretive Summary: Weaning causes a prolonged but transient change in immune gene expression in the intestine of piglets

 

Interpretive Summary: Weaning causes a prolonged but transient change in immune gene expression in the intestine of piglets

By Anne Zinn

Controlling gut inflammation is important in managing gut disorders in piglets after weaning, and establishing patterns of inflammation markers in the period of time after weaning is important for future research to determine whether interventions are effective in controlling gut inflammation in piglets. In addition, research for new strategies that promote gastrointestinal health in pigs is important because of the need to reduce antibiotic usage. A study recently published in the Journal of Animal Science aimed to evaluate the intestinal inflammatory response during the post-weaning period in piglets.

Results of the present study indicated that weaning in piglets is associated with a prolonged and transient response in gene expression of  intestinal inflammatory cytokines and an increased amount of immunoglobulin A producing cells in the intestinal tissue. These increased responses were still present at 15 and 30 days post-weaning.

The full paper can be found on the Journal of Animal Science webpage.