Interpretive Summary: Impact of manganese amino acid complex on tissue-specific trace mineral distribution and corpus luteum function in gilts
By: Dr. Emily Taylor
Manganese (Mn) is an essential element used as a cofactor for enzymes involved in synthesizing cholesterol, which is the precursor for producing steroid hormones necessary for proper reproductive function. In addition, Mn is also a component of the antioxidant enzyme Mn superoxide dismutase (MnSOD), which protects cells from oxidative damage caused by reactive oxygen species (ROS). Therefore, it protects the luteal cells from oxidative stress damage during CL regression. Mn requirements to optimize reproductive performance in the modern, highly prolific pig may be outdated. Therefore, researchers of the current study hypothesized that providing a more bioavailable source of Mn would increase CL accumulation, consequently influencing luteal function by increasing progesterone production.
Postpubertal gilts were assigned to one of four gestation diets that included a control with 20ppm of Mn in the form of Mn sulfate, or 20-, 40-, or 60ppm of Mn in the form of Mn-amino acid complex at the onset of estrus synchronization. Blood and tissue samples were collected at 12 days post estrus. Progesterone concentration increased from day 0 to 12. However, it was unaffected by dietary treatment. Luteal Mn content also increased when compared to the control. Although, CL calcium content decreased relative to the control.
In conclusion, these data support the hypothesis that feeding more bioavailable Mn will increase the Mn accumulation in the CL tissue. However, the molecular response of the CL as a result of the Mn source is unclear and may warrant further research.
This article is now available in the Journal of Animal Science.