Interpretive Summary: Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets
By: Ge Yu, Shuli Ji, Yang Yun, Kang Cheng, Hao Zhang, Peilu Jia, Tian Wang, Lili Zhang
Neonatal piglets suffer from severe birth oxidative stress due to the immaturity of their antioxidant system. In vitro and in vivo studies have now shown that the function of the antioxidant system can be modulated by bamboo leaf extract (BLE). However, the effects of BLE on the growth performance, antioxidant capacity, and hepatic apoptosis have not been explored in suckling piglets. The study’s objective was to assess the effects of BLE on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets. Suckling piglets were orally gavaged with vehicle (CON group) or 100, 200, or 300 mg BLE/kg body weight at 3 d of age for 21 d. Compared to the CON group, BLE treatment had no effects on the growth performance; BLE treatment increased antioxidant enzymes activities and antioxidant-related genes at both the gene and protein expressions in the jejunum and liver of suckling piglets; BLE treatment also inhibited hepatic apoptosis, including hepatic apoptosis rate and the expressions of apoptosis-related genes. These results indicate the efficacy of BLE to improve antioxidant capacity and inhibit hepatic apoptosis in suckling piglets, demonstrating that BLE has a certain protective effect on suckling piglets at the postnatal stage.
Read the full article in the Journal of Animal Science