January 11, 2024

Interpretive Summary: Ageratina adenophora damages the rumen epithelium via inducing the expression of inflammatory factors in goats

Interpretive Summary: Ageratina adenophora damages the rumen epithelium via inducing the expression of inflammatory factors in goats

By: Xiaoxuan Wang, Jianchen Wang, Samuel Kumi Okyere, Ruya Huang, Chenyang Shao, Muhammad Yousif, Junliang Deng, Yanchun Hu

The article aims to investigate the toxic effects of Ageratina adenophora, an invasive plant on the integrity of the rumen epithelium by measuring the changes in the expression of inflammatory factors and tight junction proteins after the consumption of A. adenophora in goats. The results showed that A. adenophora causes damage to the rumen epithelium by increasing the expression of pro-inflammatory markers like TNF-α and IFN-γ and reducing the expression of tight junction proteins such as occludin and claudin-1 in goats.

Read the full article in the Journal of Animal Science.