April 25, 2024

Interpretive Summary: Diagnostic survey of analytical methods used to determine bone mineralization in pigs

Interpretive Summary: Diagnostic survey of analytical methods used to determine bone mineralization in pigs

By: Hadley R Williams, Mike D Tokach, Jason C Woodworth, Joel M DeRouchey, Robert D Goodband, Jon R Bergstrom, Michael C Rahe, Christopher L Siepker, Panchan Sitthicharoenchai, Steve M Ensley, Scott L Radke, Jordan T Gebhardt

There is little literature or data comparing bone diagnostic results for healthy, lame, and unhealthy pigs. Typically, diagnosticians assessing clinical lameness cases in pigs will measure bone mineralization along with histopathological evaluation to diagnose and assess the severity of metabolic bone disease. Bone ash is the primary method to determine bone mineralization, with the removal of the lipid in the bone (defatting) before the bone is ashed, compared to not removing the lipid before the ashing (non-defatted). Defatting the bone reduces the amount of variation across the bones compared to non-defatting. In this diagnostic survey, there was no difference among the healthy, lame, or unhealthy pigs when comparing defatted bone ash, however, unhealthy pigs had an increased bone ash percentage compared to the healthy and lame pigs when the bones were assessed using the non-defatted procedure. There was variation across production systems and pig types for serum vitamin D. When comparing the pig types, healthy pigs had increased serum Ca, P, and vitamin D [25(OH)D3] compared to the unhealthy pigs, with the lame pigs intermediate.

Read the full article in the Journal of Animal Science.