Dietary manganese supplementation regulates lipid deposition in broiler chickens, with the liver being a significant site of lipid metabolism. This study investigated the effects of different dietary forms of supplemental manganese on hepatic lipid deposition, gene expression, and enzyme activity in the liver fat metabolism of broiler chickens. The results showed that dietary manganese supplementation decreased the hepatic lipid accumulation of broilers by inhibiting the expression of sterol-regulatory element-binding protein 1 (SREBP1) and stearoyl-coA desaturase (SCD), as well as fatty acid synthase (FAS) and malic enzyme (ME) activities, and enhancing the expression and activity of adipose triglyceride lipase (ATGL). This reduction in excessive fat production will help improve poultry health and mitigate losses in the poultry industry.

Read the full article in the Journal of Animal Science.