October 03, 2024

Interpretive Summary: Size matters: lower body weight pigs have a different response to immune challenge and amino acids supplementation above the estimated requirement compared to heavy pigs

Interpretive Summary: Size matters: lower body weight pigs have a different response to immune challenge and amino acids supplementation above the estimated requirement compared to heavy pigs

By: Graziela Alves da Cunha Valini, Steve Méthot, Candido Pomar, Luciano Hauschild, Aline Remus

An immune challenge impacts pig welfare and may decrease growth and protein deposition. These may happen due to the different nutrient requirements of immune-challenged pigs compared to non-challenged. Dietary supplementation of tryptophan, threonine, and methionine has been proven to be a strategy to mitigate performance losses by supporting immune system functioning, maintaining gut barrier integrity, and reducing oxidative status. However, individuals within a population with similar age and genetics have distinct responses to dietary strategies due to different coping abilities to an immune challenge, which may be due to body weight (BW)/body composition and feeding behavior patterns. In this context, this study investigated the effect of BW (light-weight vs. heavy-weight) and tryptophan, threonine, and methionine supplementation on feeding behavior and the coping capacity of growing pigs under an immune challenge. Heavy-weight pigs had greater feed intake regularity and coping abilities over time when compared to light-weight pigs. However, increasing the amino acid level in the diet improved feed intake regularity in light-weight pigs. The amino acid supplementation may be a potential precision nutrition strategy for light-weight pigs by improving feed intake regularity over time, reducing susceptibility to an immune challenge.

Read the full article in the Journal of Animal Science.