December 05, 2024

Interpretive Summary: The effect of repeated lipopolysaccharide endotoxin challenge on immune response of breeding ewes and subsequent lamb performance

Interpretive Summary: The effect of repeated lipopolysaccharide endotoxin challenge on immune response of breeding ewes and subsequent lamb performance

By: Molly M Austin, Briza Castro, Luis Ochoa, Jeffrey F Dominguez Arellanes, Karime L Luna, Yulianna A Salas, Sara C Gurule, Sergio Soto-Navarro, Craig A Gifford, Jennifer A Hernandez Gifford

During disease states, bacterial endotoxins act locally and systemically, negatively impacting reproductive capacity and economic productivity. The present study investigated the impacts of repeated low-dose endotoxin exposure during follicular development on the immune response and subsequent reproductive and lamb growth variables. Results indicate that bacterial endotoxin challenge during follicular development and oocyte maturation leads to reduced lamb birth weight and 60-d adjusted weaning weight.

Read the full article in the Journal of Animal Science.