Interpretive Summary: Mogroside V protects lipopolysaccharides-induced lung inflammation chicken via suppressing inflammation mediated by the Th17 through the gut-lung axis
By: Yuan Li, Kai Wang, Dan Shen, Junze Liu, Sheng Li, Luyao Liu, Kentaro Nagaoka, Chunmei Li
Frequent respiratory problems during broiler breeding not only affect the growth performance of broilers, but also jeopardize the health and safety production of broilers in serious cases. Luo Han Guo is a traditional medicinal and food plant, and its extract mogroside V (MGV) has biological functions such as blood glucose lowering, bacteriostatic, antioxidant, and antiinflammator. MGV has a great potential for the treatment of respiratory diseases, but there are fewer studies on its application in broiler farming, especially in the protection of suction health of broiler chickens, which needs to be further investigated. Therefore, this experiment was designed to investigate the specific mechanism of MGV in relieving lung inflammation in broilers and to provide theoretical basis and corresponding countermeasures for the prevention of respiratory diseases in broilers. The results showed that dietary supplementation with MGV could promote the growth performance of broilers and alleviate lipopolysaccharide-induced acute lung injury in broilers by regulating the intestinal flora to enhance the barrier function of the lungs and inhibit the development of lung inflammation.
Read the full article in the Journal of Animal Science.