Interpretive Summary: Vitamin D₃ inhibits proliferation and the early stage of adipogenic differentiation but promotes gene expression and lipid accumulation during the late stage of adipogenic differentiation in intramuscular adipose cells of Korean native cattle
By: Jun Hee Lee, Won Seob Kim, Xue Cheng Jin, Bo Mi Kim, Hong Gu Lee
This study investigated the effects of vitamin D₃ on the growth and differentiation of adipose cells derived from muscle tissue in Korean native cattle. Vitamin D₃ reduced cell proliferation during the growth phase, limiting the number of adipose cells. During early differentiation, vitamin D₃ suppressed the process of adipose cell development, but in later stages, vitamin D₃ promoted fat storage and cell maturation. These findings highlight vitamin D₃ as a potential regulator of fat deposition, offering insights for optimizing intramuscular fat in beef production.
Read the full article in the Journal of Animal Science.
