October 16, 2025

Interpretive Summary: Effects of Saccharomyces cerevisiae fermentation-derived postbiotic on methane production and plasma metabolome of fattening Holstein steers fed a high-grain diet

Interpretive Summary: Effects of Saccharomyces cerevisiae fermentation-derived postbiotic on methane production and plasma metabolome of fattening Holstein steers fed a high-grain diet

By: Anjan Dhungana, Oluwaseun A Odunfa, Alexander Altman, Ibukun Ogunade, Kyle R McLeod, Ilkyu Yoon, David L Harmon, Yun Jiang

Saccharomyces cerevisiae fermentation-derived postbiotic (SCFP) has been shown to increase ruminal pH of cattle fed a high-concentrate diet. Increased ruminal pH has been linked to increased methane emissions. Some studies have suggested that SCFP can reduce methane emissions by improving feed efficiency. In this study, we investigated how SCFP affects methane emissions in finishing beef diets and used plasma metabolomics to gain further insights into its mode of action. Supplementation of SCFP increased dry matter intake (DMI) without affecting daily methane production. Feeding SCFP increased concentrations of several blood amino acid derivatives and dipeptides, and enriched metabolic pathways associated with energy and protein metabolism.

Read the full article in the Journal of Animal Science.